Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway. Effectiveness of particle repositioning maneuvers in the treatment of benign paroxysmal positional vertigo: a systematic review. Helminski JO, Zee DS, Janssen I, Hain TC. Hashami L, Haj Mohamad Ebrahim Ketabforoush A, Nirouei M (2022) Giant cell arteritis with rare manifestations of stroke and internal carotid artery dissection: a case study. Ravandi F, Haj Mohamad Ebrahim Ketabforoush A, Azedi F, Hoshyarkhani M, Fayyaz F, Abbasi Khoshsirat N (2022) Heart failure status among acute ischemic stroke patients: a hospital-based study. A multicenter randomized double-blind study: comparison of the Epley, Semont, and sham maneuvers for the treatment of posterior canal benign paroxysmal positional vertigo. Lee JD, Shim DB, Park HJ, Song CI, Kim M-B, Kim C-H, et al. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s) author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. © Association of Otolaryngologists of India 2023. In severe forms of BPPV, betahistine or dimenhydrinate might effectively reduce the symptoms.īPPV Benign paroxysmal positional vertigo Dimenhydrinate. Older patients in the betahistine group had better social activities after treatment ( P = 0.048). There were significant differences between the females and males in emotional well-being before and after treatment in the dimenhydrinate group ( P = 0.014) and in terms of role limitation due to physical health problems in the Epley maneuver group ( P = 0.022). There was a marginally significant difference between the betahistine and dimenhydrinate groups in role limitation due to physical health problems ( P = 0.046). The original Epley maneuver was designed to be done with a healthcare provider. These movements bring the crystals back to the utricle, where they belong. There was no significant difference between the groups in age ( P = 0.753) and gender ( P = 0.050).There were significant differences in all areas of SF-36 except for social activities in the dimenhydrinate group. John Epley designed a series of movements to dislodge the crystals from the semicircular canals. SF-36 and the DHI were used before and after the treatment. Patients received betahistine 8 mg TDS or dimenhydrinate 50 mg once daily plus Epley or the Epley alone for four weeks. 90 adult patients diagnosed with BPPV in hospitals and ENT clinics were selected through convenience sampling. This prospective cohort study was performed in Mashhad, Iran, from 2013 to 2015. This study was designed to compare betahistine and dimenhydrinate plus the Epley maneuver and the Epley maneuver alone. Although the Epley maneuver is considered the primary treatment in BPPV, anti-vertigo medications are effective in residual symptoms.
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